VeriNA3d

VeriNA3d analyzes nucleic acids structural data as an R package for detailed characterization and large-scale analysis of RNA and other nucleic acid structures.

Key Features:

• Single-Structure Analysis: Performs detailed analysis of individual nucleic acid structures to extract structural characteristics and properties.
• Dataset Handling: Parses and processes mmCIF and PDB files and manages large collections of structures for batch analyses.
• Data Mining Capabilities: Implements functions for mining nucleic acids structural databases to enable high-throughput and flexible exploration of complex RNA structures across datasets.

Scientific Applications:

• RNA structure–function analysis: Enables detailed examination of RNA structure–function relationships using per-structure and comparative metrics.
• High-throughput structural screening: Supports high-throughput screening and systematic comparison of nucleic acid structures across large mmCIF/PDB datasets.
• Database integration for analysis: Facilitates integration with structural databases to aggregate and analyze collections of nucleic acid structures.

Methodology:

Parses mmCIF and PDB formats and applies per-structure analyses together with dataset-level mining functions for single-structure and large-scale comparative analyses.