VisFeature

VisFeature visualizes and analyzes statistical features derived from DNA, RNA, and protein primary sequences to support prediction of functional attributes of genes and proteins.


Key Features:

  • Visualization of statistical features: Generates visual representations of statistical attributes derived from biological sequences to aid interpretation of feature patterns.
  • Sequence data retrieval: Performs retrieval of sequence data for downstream feature extraction and analysis.
  • Multiple sequence alignment: Supports alignment of multiple sequences to inform comparative feature analysis.
  • Statistical feature generation: Computes statistical features from primary sequences for use in predictive analyses.
  • Supported sequence types: Explicitly handles DNA, RNA, and protein sequences for feature extraction and analysis.
  • Functional attribute prediction: Uses derived statistical features to infer potential functional characteristics of genes and proteins.
  • Implementation technologies: Implements computational components using JavaScript/Electron and R.

Scientific Applications:

  • Predict functional attributes: Infers potential functional properties of genes and proteins from sequence-derived statistical features.
  • Enhance sequence analysis: Integrates sequence retrieval and multiple sequence alignment to prepare data for feature extraction and comparative analyses.
  • Genomics and proteomics studies: Supports interpretation of genomic and proteomic sequence data through statistical feature analysis.

Methodology:

Uses JavaScript/Electron and R and performs sequence data retrieval, multiple sequence alignment, and generation of statistical features.

Details

License:
GPL-3.0
Programming Languages:
JavaScript, R, C++
Added:
11/14/2019
Last Updated:
1/2/2021

Operations

Publications

Wang J, Du P, Xue X, Li G, Zhou Y, Zhao W, Lin H, Chen W. VisFeature: a stand-alone program for visualizing and analyzing statistical features of biological sequences. Bioinformatics. 2019;36(4):1277-1278. doi:10.1093/bioinformatics/btz689. PMID:31504195.

PMID: 31504195
Funding: - National Key R&D Program of China: 2018YFC0910405 - National Natural Science Foundation of China: 31771471, NSFC 61872268 - Natural Science Foundation for Distinguished Young Scholar of Hebei Province: C2017209244 - CAS Key Lab of Network Data Science and Technology, Institute of Computing Technology, Chinese Academy of Sciences: CASNDST201705

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