XenMine

XenMine integrates and enables querying and analysis of heterogeneous biological data for Xenopus tropicalis and Xenopus laevis.

Key Features:

• Data Integration: Uses InterMine's extensible data model to aggregate and integrate heterogeneous biological data related to Xenopus species.
• Customizable Query Facility: Provides a configurable query builder that supports precise searches including genomic region searches across the genomes of Xenopus tropicalis and Xenopus laevis.
• Statistical Analysis Tools: Includes widget-based statistical analysis modules for in-platform evaluation of query results.
• Data Export Options: Supports export of query and analysis results in multiple commonly used bioinformatics file formats.
• Extensibility and Customization: Permits developers to add new tools, analyses, and data types via the extensible framework.
• Web Services and Programming Support: Exposes web services and provides client libraries in five commonly used programming languages for integration with computational workflows.

Scientific Applications:

• Genetics, Development and Physiology: Facilitates studies of genetics, development, and physiology in Xenopus tropicalis and Xenopus laevis by integrating relevant datasets.
• Genomic Research: Enables basic genomic research and targeted genomic region analyses across the two Xenopus genomes.
• Functional Genomics: Supports functional genomics investigations, including identification of genetic pathways and regulatory networks.
• Phenotype Analysis: Assists analysis of phenotypic expressions associated with genetic variation in Xenopus species.

Methodology:

XenMine aggregates and integrates heterogeneous biological data sources into a cohesive database structure using InterMine's extensible framework, and provides a query builder and analysis tools designed to handle complex queries efficiently.