ZebraSTM

ZebraSTM quantifies spontaneous tail movement (STM) in zebrafish embryos to provide objective measurements for assessing behavioral responses in neurotoxicity studies.


Key Features:

  • Automated video analysis: Automates quantification of STM across multiple zebrafish embryos using recorded video data.
  • MATLAB implementation: Implemented as a MATLAB script for data processing and analysis.
  • Movement extraction: Processes video recordings to extract relevant movement data that reflect spontaneous tail activity (STM).

Scientific Applications:

  • Neurotoxicity assessment: Quantifies STM to evaluate behavioral changes resulting from chemical exposure in zebrafish embryos.
  • Chemical screening: Enables assessment of environmental toxins and pharmaceutical compounds for potential neurobehavioral effects.

Methodology:

Implemented as a MATLAB script that processes video recordings of zebrafish embryos and extracts movement data reflecting spontaneous tail activity.

Topics

Details

License:
CC-BY-4.0
Maturity:
Mature
Cost:
Free of charge
Tool Type:
command-line tool
Operating Systems:
Linux, Windows, Mac
Programming Languages:
MATLAB
Added:
5/27/2019
Last Updated:
6/16/2020

Operations

Publications

González-Fraga J, Dipp-Alvarez V, Bardullas U. Quantification of Spontaneous Tail Movement in Zebrafish Embryos Using a Novel Open-Source MATLAB Application. Zebrafish. 2019;16(2):214-216. doi:10.1089/zeb.2018.1688. PMID:30615594.