a4Classif

a4Classif performs classification of Affymetrix microarray gene expression data using machine learning to support interpretation of microarray experiment results.


Key Features:

  • Machine Learning Integration: Incorporates a variety of machine learning techniques tailored for classification of gene expression profiles.
  • Affymetrix Microarray Analysis: Handles Affymetrix microarray gene expression datasets as primary input for classification and interpretation.
  • Bioconductor Interoperability: Integrates with the Bioconductor project to interoperate with other Bioconductor packages.

Scientific Applications:

  • Genomics Research: Enables disease classification, biomarker discovery, and analysis of gene regulatory mechanisms from classified gene expression data.
  • Molecular Biology Studies: Assists interpretation of complex gene expression patterns to inform investigations of cellular processes.

Methodology:

Implemented in R and applying machine learning classification algorithms to process and interpret Affymetrix microarray gene expression data, with integration into the Bioconductor ecosystem.

Topics

Collections

Details

License:
GPL-3.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

Documentation

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