AagingBase

AagingBase provides a curated database of experimentally validated anti-aging peptides and computed physicochemical and structural properties to support peptide-based anti-aging research.

Key Features:

• Extensive Collection: Contains 282 experimentally validated anti-aging peptides compiled from 54 research articles and 236 patents.
• Comprehensive Physicochemical Analysis: Employs computational techniques to calculate amino acid composition, instability index, hydrophobic areas, and related physicochemical properties.
• Detailed Informative Analyses: Provides atomic composition, secondary structure fractions, tertiary structure information, and amino acid composition frequencies for each peptide.
• Advanced Search and Filtering Options: Offers advanced search and filtering to retrieve peptides that meet specified criteria.
• Similarity Search Functionality: Includes a similarity search to identify peptides with related sequences or properties.

Scientific Applications:

• Identifying Potential Therapeutic Candidates: Enables prioritization of peptide candidates based on computed physicochemical and structural properties.
• Facilitating Drug Discovery and Development: Supports screening and evaluation of anti-aging peptides for drug discovery workflows.
• Advancing Geriatric Medicine Research: Provides data and analyses to inform development of age-related therapies and geriatric research.

Methodology:

Collects experimentally validated peptides from research articles and patents and applies computational physicochemical and structural analyses (amino acid composition, instability index, hydrophobic areas, atomic composition, secondary structure fractions, tertiary structure assessments) and similarity searches.