ADAT

ADAT parses and visualizes proteomic data from SOMAscan™ ADAT files to support quality control and preliminary statistical analysis.

Key Features:

• ADAT parsing: Parses the proprietary text-based ADAT (Adipose Derived Analysis Text) format produced by the SOMAscan™ assay to access proteomic measurements.
• Data visualization: Generates a variety of plots for exploratory visualization of proteomic data.
• Quality control (QC): Provides built-in QC functions to assess data quality and integrity prior to downstream analysis.
• Statistical analysis: Includes integrated statistical functions for preliminary analyses of SOMAscan™ proteomic datasets.

Scientific Applications:

• Proteomic data exploration: Exploration and visualization of protein expression measurements derived from SOMAscan™ assays across samples.
• Data quality assessment: Detection of technical issues and assessment of sample/data integrity using QC metrics derived from ADAT content.
• Preliminary statistical analysis and hypothesis generation: Initial statistical interrogation of proteomic data to inform experimental design and downstream analyses.

Methodology:

Implemented in R using the Shiny framework for processing SOMAscan™ ADAT files, performing QC, visualization, and basic statistical analyses.