admixr

admixr provides an R interface to ADMIXTOOLS for executing f3, D-statistics, f4, f4-ratio, qpWave, and qpAdm analyses and for automating configuration and output parsing to support reproducible population genetic inference on EIGENSTRAT-format data.


Key Features:

  • ADMIXTOOLS integration: Integrates ADMIXTOOLS functionality into R to run f3, D-statistics, f4, f4-ratio, qpWave, and qpAdm analyses.
  • Configuration and output automation: Automates generation of ADMIXTOOLS configuration files and parsing of program output.
  • Reproducibility: Unifies analysis steps within an R framework to enable reproducible analytic workflows.
  • EIGENSTRAT data manipulation: Provides R functions to process, filter, and manipulate datasets in EIGENSTRAT format.

Scientific Applications:

  • Evolutionary biology: Detects admixture events and infers evolutionary relationships using f-statistics and qpAdm/qpWave analyses.
  • Anthropology: Investigates population structure and migration patterns by applying D-statistics and related tests.
  • Conservation genetics: Assesses gene flow and admixture in non-human populations to inform conservation and management decisions.

Methodology:

admixr integrates ADMIXTOOLS into R and automates configuration file generation and output parsing, and it provides functions to process, filter, and manipulate EIGENSTRAT-format datasets.

Topics

Details

License:
CC-BY-4.0
Maturity:
Mature
Cost:
Free of charge
Tool Type:
library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
5/22/2019
Last Updated:
6/16/2020

Operations

Publications

Petr M, Vernot B, Kelso J. <i>admixr</i>—R package for reproducible analyses using ADMIXTOOLS. Bioinformatics. 2019;35(17):3194-3195. doi:10.1093/bioinformatics/btz030. PMID:30668635. PMCID:PMC6736366.

Documentation