admixr
admixr provides an R interface to ADMIXTOOLS for executing f3, D-statistics, f4, f4-ratio, qpWave, and qpAdm analyses and for automating configuration and output parsing to support reproducible population genetic inference on EIGENSTRAT-format data.
Key Features:
- ADMIXTOOLS integration: Integrates ADMIXTOOLS functionality into R to run f3, D-statistics, f4, f4-ratio, qpWave, and qpAdm analyses.
- Configuration and output automation: Automates generation of ADMIXTOOLS configuration files and parsing of program output.
- Reproducibility: Unifies analysis steps within an R framework to enable reproducible analytic workflows.
- EIGENSTRAT data manipulation: Provides R functions to process, filter, and manipulate datasets in EIGENSTRAT format.
Scientific Applications:
- Evolutionary biology: Detects admixture events and infers evolutionary relationships using f-statistics and qpAdm/qpWave analyses.
- Anthropology: Investigates population structure and migration patterns by applying D-statistics and related tests.
- Conservation genetics: Assesses gene flow and admixture in non-human populations to inform conservation and management decisions.
Methodology:
admixr integrates ADMIXTOOLS into R and automates configuration file generation and output parsing, and it provides functions to process, filter, and manipulate EIGENSTRAT-format datasets.
Topics
Details
- License:
- CC-BY-4.0
- Maturity:
- Mature
- Cost:
- Free of charge
- Tool Type:
- library
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- R
- Added:
- 5/22/2019
- Last Updated:
- 6/16/2020
Operations
Publications
Petr M, Vernot B, Kelso J. <i>admixr</i>—R package for reproducible analyses using ADMIXTOOLS. Bioinformatics. 2019;35(17):3194-3195. doi:10.1093/bioinformatics/btz030. PMID:30668635. PMCID:PMC6736366.
PMID: 30668635