affyPara

affyPara performs parallelized exploratory analysis of oligonucleotide array data to accelerate preprocessing, normalization, and interpretation of high-throughput microarray gene expression datasets.


Key Features:

  • Parallelization: Distributes computations across multiple processors to reduce computation time for large oligonucleotide microarray datasets.
  • Integration with Bioconductor: Provides an R package compatible with the Bioconductor project for use within the Bioconductor ecosystem.
  • Interoperability: Interoperates with other Bioconductor packages to combine preprocessing, normalization, and downstream statistical analyses.
  • Community-Driven Development: Developed and contributed by the community with initial review and continuous automated testing.

Scientific Applications:

  • Microarray Data Analysis: Facilitates preprocessing, normalization, and exploratory analysis of microarray (oligonucleotide array) gene expression data.
  • High-Throughput Data Processing: Supports analysis of large-scale genomics datasets for studies of gene regulation, disease mechanisms, and biomarker identification.

Methodology:

Parallel computing (distributing tasks across multiple processors), preprocessing, normalization, exploratory analysis, and advanced statistical methods tailored for high-throughput microarray data.

Topics

Collections

Details

License:
GPL-3.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

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