Atlas of Inflammation-Resolution (AIR)

Atlas of Inflammation-Resolution (AIR) provides a standardized, multi-layered resource compiling molecular interactions and process diagrams to represent acute inflammation and its resolution.

Key Features:

• Comprehensive Data Integration: Compiles thousands of molecular interactions into interconnected multi-layered process diagrams encompassing clinically relevant phenotypes.
• Interdisciplinary Data Integration: Integrates data from diverse biomedical domains to represent interdisciplinary aspects of inflammation dynamics.
• Visualization (Minerva): Uses the Minerva platform to visualize complex biological data and map experimental data onto inflammation-resolution processes.
• Standardized Encoding: Encodes molecular details using international standards to ensure consistency and interoperability with other bioinformatics resources.

Scientific Applications:

• Research Support: Supports hypothesis formulation and validation by providing detailed maps of inflammation-related interactions.
• Clinical Decision Making: Assists interpretation of disease mechanisms and therapeutic actions by integrating molecular and phenotype data.
• Educational Resource: Provides structured representations of inflammation biology for education and training.

Methodology:

Compilation of thousands of molecular interactions into interconnected multi-layered process diagrams; visualization via the Minerva platform; molecular details encoded using international standards.