Allergome

Allergome consolidates curated information on allergenic molecules, integrating literature-derived annotations for over 1,500 proteins identified as allergens to support allergy research and allergen identification.

Key Features:

• Data Integration and Organization: Systematically compiles and curates data from peer-reviewed scientific literature, organizing information on over 1,500 proteins identified as allergens.
• Interconnectivity Tools: Provides cross-referencing and historical-tracking tools including InterAll, ReTiME (Reference Time Machine), RefArray, and AllergomeBlaster for interoperability and literature mapping.
• Bioinformatics Applications: Applies bioinformatics methods to integrate experimental, clinical, and epidemiologic datasets for comparative analysis of allergens.
• Research Applications: Supports identification and analysis of potential allergenicity in new compounds and facilitates basic and translational allergy research.

Scientific Applications:

• Allergen identification and annotation: Uses the consolidated database and tools such as AllergomeBlaster to identify and annotate potential allergenic proteins and compounds.
• Literature-based analysis and meta-research: Enables cross-referencing, reference arraying, and temporal tracking of publications via InterAll, RefArray, and ReTiME to support meta-analyses and mechanistic studies.

Methodology:

Curates data from peer-reviewed scientific literature and utilizes bioinformatics tools to analyze and integrate diverse experimental, clinical, and epidemiologic datasets.