AltWOA

AltWOA performs feature selection on high-dimensional DNA microarray gene expression datasets using an altruistic variant of the Whale Optimization Algorithm to identify relevant biomarker genes.


Key Features:

  • Altruistic Whale Optimization Algorithm: Extends the Whale Optimization Algorithm (WOA) by incorporating altruistic behavior among candidate solutions to improve convergence toward optimal feature subsets.
  • High-Dimensional Feature Selection: Selects informative genes from large DNA microarray gene expression datasets while eliminating non-informative features.
  • Meta-Heuristic Optimization: Applies a population-based meta-heuristic search strategy to explore complex feature spaces and identify optimal gene subsets.

Scientific Applications:

  • Biomarker Discovery: Identifies disease-associated genes in DNA microarray datasets.
  • Cancer Genomics: Detects gene expression features associated with different cancer types.
  • High-Dimensional Data Analysis: Supports dimensionality reduction and feature selection in genomic datasets.

Methodology:

AltWOA models the bubble-net feeding behavior of humpback whales through the Whale Optimization Algorithm and introduces altruistic interactions among candidate solutions to propagate promising feature subsets during optimization.

Topics

Details

License:
MIT
Cost:
Free of charge
Tool Type:
workflow
Operating Systems:
Windows
Programming Languages:
Python
Added:
6/20/2022
Last Updated:
6/20/2022

Operations

Publications

Kundu R, Chattopadhyay S, Cuevas E, Sarkar R. AltWOA: Altruistic Whale Optimization Algorithm for feature selection on microarray datasets. Computers in Biology and Medicine. 2022;144:105349. doi:10.1016/j.compbiomed.2022.105349. PMID:35303580.