AltWOA
AltWOA performs feature selection on high-dimensional DNA microarray gene expression datasets using an altruistic variant of the Whale Optimization Algorithm to identify relevant biomarker genes.
Key Features:
- Altruistic Whale Optimization Algorithm: Extends the Whale Optimization Algorithm (WOA) by incorporating altruistic behavior among candidate solutions to improve convergence toward optimal feature subsets.
- High-Dimensional Feature Selection: Selects informative genes from large DNA microarray gene expression datasets while eliminating non-informative features.
- Meta-Heuristic Optimization: Applies a population-based meta-heuristic search strategy to explore complex feature spaces and identify optimal gene subsets.
Scientific Applications:
- Biomarker Discovery: Identifies disease-associated genes in DNA microarray datasets.
- Cancer Genomics: Detects gene expression features associated with different cancer types.
- High-Dimensional Data Analysis: Supports dimensionality reduction and feature selection in genomic datasets.
Methodology:
AltWOA models the bubble-net feeding behavior of humpback whales through the Whale Optimization Algorithm and introduces altruistic interactions among candidate solutions to propagate promising feature subsets during optimization.
Topics
Details
- License:
- MIT
- Cost:
- Free of charge
- Tool Type:
- workflow
- Operating Systems:
- Windows
- Programming Languages:
- Python
- Added:
- 6/20/2022
- Last Updated:
- 6/20/2022
Operations
Publications
Kundu R, Chattopadhyay S, Cuevas E, Sarkar R. AltWOA: Altruistic Whale Optimization Algorithm for feature selection on microarray datasets. Computers in Biology and Medicine. 2022;144:105349. doi:10.1016/j.compbiomed.2022.105349. PMID:35303580.
PMID: 35303580