Animal Metabolite Database

Animal Metabolite Database provides access to quantitative metabolomics data across animal tissues to enable comparison and analysis of metabolite concentrations for biomedical, evolutionary, and environmental research.

Key Features:

• Quantitative metabolomics repository: Stores quantitative metabolomic datasets focused on metabolite concentrations rather than raw experimental data.
• Tissue and species coverage: Contains extensive data primarily for vertebrate eye lenses and blood, and additionally for muscle, heart, liver, brain, spanning wild species native to Siberia and laboratory rodents.
• Standardized concentration reporting: Reports metabolite concentrations in nanomoles per gram of wet tissue weight (nmol/g) for consistent comparison across samples and studies.
• Per-sample metabolite coverage: Individual samples typically report concentrations of 60–90 key metabolites.
• Built-in statistical analysis: Integrates built-in statistical analysis tools for browsing and analyzing metabolite concentration data.
• Data deposition and exchange: Supports deposition and exchange of quantitative metabolomic datasets.

Scientific Applications:

• Animal disease modeling: Provides baseline metabolite concentrations for use in animal models of human diseases.
• Assessment of medical formulations: Enables evaluation of how medical formulations affect metabolic processes.
• Evolutionary studies: Facilitates investigation of metabolic adaptations across species.
• Environmental studies: Allows analysis of how external factors influence metabolite levels in animal tissues.
• Comparative metabolomics: Supports comparison of metabolic profiles across studies, tissues, and species.

Methodology:

Uses built-in statistical analysis tools on deposited quantitative metabolomic datasets with concentrations reported in nmol/g and supports dataset deposition and exchange.