ANCESTRYMAP

ANCESTRYMAP finds skews in ancestry that are potentially associated with disease genes in recently mixed populations. Admixture mapping is a method for localizing disease causing genetic variants that differ in frequency across populations. It is most advantageous to apply this approach to populations that have descended from a recent mix of two ancestral groups that have been geographically isolated.

Topics

Details

Tool Type:
command-line tool
Operating Systems:
Linux
Programming Languages:
Perl, C
Added:
12/18/2017
Last Updated:
4/14/2021

Operations

Publications

Patterson N, Hattangadi N, Lane B, Lohmueller KE, Hafler DA, Oksenberg JR, Hauser SL, Smith MW, O’Brien SJ, Altshuler D, Daly MJ, Reich D. Methods for High-Density Admixture Mapping of Disease Genes. The American Journal of Human Genetics. 2004;74(5):979-1000. doi:10.1086/420871. PMID:15088269. PMCID:PMC1181990.

Documentation

Links