annotate

annotate annotates genomic data within R by providing gene and regulatory element annotations through Bioconductor package resources for high-throughput genomics analysis.


Key Features:

  • Integration with Bioconductor: Operates within the Bioconductor framework in R and leverages a suite of 934 interoperable packages.
  • Interoperability: Interacts with diverse datasets and analytical tools across the Bioconductor ecosystem to enable combined analyses.
  • Genomic annotation: Provides annotations that identify gene functions, regulatory elements, and other biological features of genomic sequences.
  • High-throughput data processing: Employs R-based statistical computations and advanced algorithms to process high-throughput genomic data.
  • Community-driven development: Is part of the Bioconductor community subject to formal initial reviews and ongoing automated testing.

Scientific Applications:

  • Comprehensive genomic annotation: Annotates genes and regulatory elements to support interpretation of genomic sequences.
  • Gene expression and variant analysis: Supports exploration of gene expression patterns and identification of genetic variants and their functional implications.
  • Bioconductor workflow integration: Integrates annotation results into broader Bioconductor-based genomics workflows for downstream statistical and bioinformatic analyses.

Methodology:

Performs R-based statistical computations and applies advanced algorithms to process high-throughput genomic data using Bioconductor packages.

Topics

Collections

Details

License:
Artistic-2.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Data Inputs & Outputs

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

Documentation

Downloads