Arena3Dweb

Arena3Dweb visualizes multi-layered graphs in three-dimensional space to enable exploration and integration of complex network relationships.

Key Features:

• Interactive 3D Visualization: Visualizes multiple networks simultaneously within a single 3D view and represents both intra-layer and inter-layer connections.
• Customizable Layouts: Provides multiple layout algorithms that can be applied to selected layers individually or in combination.
• Dynamic Manipulation: Supports translation, rotation, and scaling of individual layers and the entire 3D scene.
• Visual Customization: Allows customization of node and edge attributes including colors, positions, and sizes.
• Support for Graph Types: Accommodates weighted and unweighted undirected graphs.

Scientific Applications:

• Biomedical data integration: Integrates heterogeneous biomedical datasets into coherent multi-layer network representations.
• Drug repurposing for SARS-CoV-2: Applied in case studies for drug repurposing research related to SARS-CoV-2.
• GPCR signaling in melanoma: Used to analyze GPCR signaling pathways implicated in melanoma.

Methodology:

Implemented using R, Shiny, and JavaScript.