ARIES

ARIES provides Galaxy-based workflows and infrastructure for analysis, management, and integration of Next Generation Sequencing (NGS) and Whole-Genome Sequencing (WGS) data in molecular epidemiology and genomic research.

Key Features:

• Galaxy Framework Integration: Implemented as an instance of the Galaxy framework to provide workflow composition and execution for bioinformatic analyses.
• NGS and WGS Support: Supports analysis and management of genomic data derived from Next Generation Sequencing (NGS) and Whole-Genome Sequencing (WGS).
• Workflow Engine for IRIDA: Operates as a workflow engine within the Integrated Rapid Infectious Disease Analysis (IRIDA) platform.
• Reproducibility and Transparency: Enables reproducible and transparent data analysis through managed workflows and standardized execution environments.
• Large-scale Dataset Management: Designed to manage and analyze large-scale genomic datasets for molecular epidemiology studies.
• Web Service Deployment: Can be deployed as a web service and as a workflow execution engine for integrated genomic analyses.

Scientific Applications:

• Molecular Epidemiology: Analysis and integration of NGS and WGS data for molecular epidemiology and infectious disease genomic investigations.
• Microbial Genomics: Genomic analysis of microbial genomes derived from NGS/WGS for research in microbiology and related fields.

Methodology:

Implemented as a Galaxy instance and integrated as a workflow engine for IRIDA to combine data collection, processing, and analysis within a single environment.