ARP wARP

ARP wARP automates macromolecular model building from crystallographic diffraction data to construct and complete protein, RNA/DNA, secondary structure, side chain, loop, solvent, and ligand models.

Key Features:

• Automated Model Building: ARP wARP automates construction and completion of macromolecular models from crystallographic diffraction data.
• Comprehensive Modeling Capabilities: Supports proteins, RNA/DNA, secondary structures, side chains, loops, solvent molecules, and ligands.
• Advanced Algorithms: Employs algorithms to interpret complex crystallographic diffraction data objectively and reproducibly.
• Integration with ArpNavigator: Interfaces with the molecular viewer ArpNavigator.

Scientific Applications:

• Structural Biology Research: Interprets crystallographic data to build macromolecular models for understanding molecular structure and function.
• Drug Discovery and Development: Models ligands and solvent molecules to support analysis of protein–ligand interactions relevant to drug design.
• Biophysical Studies: Provides macromolecular structures for studies of physical properties and molecular dynamics.

Methodology:

ARP wARP employs advanced algorithms to automate interpretation of crystallographic diffraction data and macromolecular model construction. The software integrates with the molecular viewer ArpNavigator.