AthRiboNC

AthRiboNC identifies ncRNAs with coding potential in Arabidopsis thaliana using Ribo-seq data and provides analysis of their expression, co-expression networks, and module enrichment.

Key Features:

• ncRNA Coding Potential Identification: Analyzes Ribo-Seq data from 226 Arabidopsis thaliana samples to identify open reading frames within ncRNAs.
• Comprehensive ncRNA Coverage: Contains 2743 long non-coding RNAs, 255 microRNAs, and 1871 circular RNAs with 40,162 identified ORFs.
• Co-expression Network Analysis: Constructs co-expression networks for ncRNAs with coding potential to reveal correlations and potential biological function interpretations.
• Expression Analysis: Provides analysis of expression patterns for ncRNAs with coding potential.
• Module Enrichment Analysis: Performs module enrichment analysis to interpret potential biological functions.

Scientific Applications:

• Plant ncRNA Translation Research: Supports systematic exploration of translational activities of plant ncRNAs containing small open reading frames.
• Small Peptide Discovery: Facilitates identification of biologically functional small peptides encoded by sORFs within ncRNAs.
• Functional Annotation of ncRNAs: Enables interpretation of biological functions through co-expression network and module enrichment analysis.

Methodology:

Collection and analysis of Ribo-Seq data from 226 Arabidopsis thaliana samples.