BactEXTRACT
BactEXTRACT converts raw microtitre plate reader optical density, fluorescence, and luminescence measurements into analyses and publication-ready visualizations of bacterial growth and gene expression.
Key Features:
- Data types supported: Processes raw optical density, fluorescence, and luminescence measurements acquired from microtitre plate readers.
- Growth-curve and expression analysis: Derives bacterial growth curves and gene expression profiles from processed measurement data.
- Visualization and export: Produces publication-ready plots directly from processed datasets.
Scientific Applications:
- Microbial physiology: Quantifies growth kinetics and population behavior from optical density measurements.
- Genetics: Assesses gene expression changes using fluorescence and luminescence reporter measurements.
- Systems biology: Integrates growth and expression measurements to support comparative and systems-level analyses across strains or conditions.
Methodology:
Converts and processes raw optical density, fluorescence, and luminescence measurements from microtitre plate readers into processed datasets and publication-ready plots.
Topics
Details
- Cost:
- Free of charge
- Tool Type:
- web application
- Operating Systems:
- Mac, Linux, Windows
- Programming Languages:
- R
- Added:
- 4/19/2024
- Last Updated:
- 11/24/2024
Operations
Publications
Dénéréaz J, Veening J. BactEXTRACT: an R Shiny app to quickly extract, plot and analyse bacterial growth and gene expression data. Access Microbiology. 2024;6(1). doi:10.1099/acmi.0.000742.v3. PMID:38361656. PMCID:PMC10866030.
PMID: 38361656
PMCID: PMC10866030
Funding: - European Research Council: 771534-PneumoCaTChER
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung: 310030_192517, 310030_200792, 51NF40_180541