BALDR
BALDR performs automated comparison and prioritization of biomarker candidates for type 2 diabetes mellitus by integrating protein, gene, disease-related, text-mined, and experimental data from human and mouse IMI2 RHAPSODY studies.
Key Features:
- Comprehensive data integration: Aggregates protein, gene, and disease-related information from major public repositories alongside text-mining outputs and experimental datasets from human and mouse IMI2 RHAPSODY studies.
- Automated pipeline: Automates comparison and prioritization of biomarker candidates across integrated datasets.
- Comparative outputs: Generates comparative analyses presented as figures and tables enabling direct comparison of up to 20 biomarker candidates.
- Evidence integration: Combines computational text-mining evidence with experimental results to support data-driven prioritization.
Scientific Applications:
- Biomarker discovery and prioritization: Assists identification and ranking of promising biomarkers for type 2 diabetes mellitus using integrated multi-source evidence.
- Candidate selection for validation: Supports selection and resource prioritization for downstream experimental verification of biomarker candidates.
Methodology:
Systematic data integration and analysis using computational text-mining techniques and experimental datasets, processed by an automated pipeline to produce comparative analyses.
Topics
Details
- Cost:
- Free of charge
- Tool Type:
- web application
- Operating Systems:
- Mac, Linux, Windows
- Programming Languages:
- R
- Added:
- 2/26/2024
- Last Updated:
- 11/24/2024
Operations
Publications
Lundgaard AT, Burdet F, Siggaard T, Westergaard D, Vagiaki D, Cantwell L, Röder T, Vistisen D, Sparsø T, Giordano GN, Ibberson M, Banasik K, Brunak S. BALDR: A Web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus. PLOS Computational Biology. 2023;19(8):e1011403. doi:10.1371/journal.pcbi.1011403. PMID:37590326. PMCID:PMC10464978.