BaSDAS

BaSDAS analyzes pooled knockout screening Barcode-Seq data to provide statistical analysis and visualization for functional genomics studies.

Key Features:

• Barcode-Seq data processing: Processes Barcode-Seq data generated from pooled knockout screens to enable downstream analysis.
• Support for diverse libraries: Supports pooled screening libraries derived from yeast, human, and mouse models.
• Comprehensive statistical functions: Implements robust statistical analyses for interpreting knockout screen results.
• Advanced visualization tools: Produces visualization outputs to present and interpret genomic screening results.

Scientific Applications:

• Genome-wide screening studies: Facilitates analysis of pooled knockout screens to identify essential genes and pathways.
• Functional genomics: Supports inference of gene function and genetic interactions from barcode-based screens.
• Drug discovery: Aids identification of potential therapeutic targets based on functional genomics screening data.

Methodology:

Analyzes Barcode-Seq data from pooled knockout screens and applies statistical analysis combined with visualization.