BASE

BASE provides a platform to store, annotate, track, and analyze large-scale microarray experiment data to support reproducible genomic research.

Key Features:

• Comprehensive Data Repository: Stores annotable local microarray experiment data and tracks biomaterials from biosource through sample collection, extraction, labeling, raw data, and analyses.
• Annotation Capabilities: Allows annotations on all items that can be used as experimental factors in downstream analysis.
• Information Management System: Records and links every component and metadata of microarray experiments to maintain data provenance.
• Adaptability and Extensibility: Supports a wide range of experimental setups and extension/customization of the existing infrastructure.

Scientific Applications:

• Asynchronous and long-term microarray studies: Centralizes data management to enable re-analysis as additional samples become available.
• Experimental factor analysis: Uses detailed annotations as experimental factors in downstream analyses of microarray data.
• Reproducibility and provenance tracking: Facilitates systematic use of collected data to enhance reproducibility and reliability of genomic experiments.

Methodology:

Integrates and tracks information from biosources through sample collection, extraction, labeling, raw data capture, and final analyses, storing annotations that can be used as experimental factors.