basico

basico provides a Python interface to COPASI for creating, editing, simulating, and analyzing computational models of biological systems.

Key Features:

• Model creation and editing: Create new COPASI models and modify existing models using Python scripts.
• Simulation and analysis: Invoke COPASI simulations and perform analyses including parameter estimation, sensitivity analysis, optimization, and model fitting.
• Automation: Automate repetitive or large-scale model manipulation and analysis workflows via Python scripting.
• Custom scripting: Implement custom Python scripts for specialized analyses such as model identification and other operations beyond standard COPASI functionality.

Scientific Applications:

• Understanding complex systems: Simulate and analyze biological system dynamics to investigate system behavior under varying conditions.
• Drug target prediction: Simulate scenarios and explore parameter spaces to support prediction of potential drug targets or perturbation effects.
• Advanced computational biology: Extend COPASI capabilities through scripting for advanced model development, analysis, and method development.

Methodology:

Uses Python scripting to create and edit COPASI models and to invoke COPASI simulations and analyses, including parameter estimation, sensitivity analysis, optimization, model fitting, and model identification.