BASys2

BASys2 performs rapid bacterial genome annotation by leveraging over 30 bioinformatics tools and 10 databases to identify all gene types and generate up to 62 annotation fields per gene or protein.

Key Features:

• Comprehensive Gene Annotation: Generates up to 62 annotation fields per gene/protein by utilizing over 30 bioinformatics tools and 10 different databases.
• Metabolome Annotation: Provides extensive support for whole metabolome annotation.
• Structural Proteome Generation: Supports complete structural proteome generation.
• Interactive Genome Visualization: Enables rapid, dynamic visualization of complete bacterial genome maps with multiple concentric annotation tracks, color-coded legends, and individual gene and metabolite annotation viewing.
• Input Flexibility: Accepts both FASTA and FASTQ file formats.
• Deployment Options: Available as a web server, desktop viewer application, and locally installable Docker image.

Scientific Applications:

• Bacterial Genome Annotation: Identifies all gene types and generates comprehensive functional annotations for bacterial genomes.
• Metabolome Analysis: Supports whole metabolome annotation to characterize metabolic capabilities of bacterial organisms.
• Structural Proteomics: Enables complete structural proteome generation for studying protein structures at genome scale.

Methodology:

BASys2 employs a fast genome-matching and a novel annotation transfer strategy to reduce annotation time, leveraging over 30 bioinformatics tools and 10 different databases.