BellaVista

BellaVista enables interactive visualization and exploration of imaging-based spatial transcriptomics data at subcellular resolution.

Key Features:

• Multi-platform data support: Natively supports Xenium (10x Genomics), MERSCOPE (Vizgen), and custom MERFISH platforms.
• Simultaneous multi-layer visualization: Provides simultaneous visualization of images, transcripts, and cell segmentation boundaries.
• Interactive exploration: Facilitates visualization, quality control, and custom spatial analysis of spatial transcriptomics datasets.

Scientific Applications:

• Tissue organization analysis: Enables analysis of tissue organization across scales from molecules to entire organs.
• Gene expression localization: Supports locating and identifying individual RNA molecules in situ to reveal gene expression patterns.
• Quality control: Facilitates quality control of imaging-based spatial transcriptomics datasets.
• Custom spatial analysis: Supports user-defined spatial analyses of imaging-based spatial transcriptomics data.

Methodology:

BellaVista is a lightweight open-source tool that provides interactive visualization of images, transcripts, and cell segmentation boundaries for imaging-based spatial transcriptomics data.