BENviewer

BENviewer visualizes gene interaction networks using graph embedding models to produce two-dimensional representations of biological pathways that reveal genes and the tightness and nature of their interactions.


Key Features:

  • Graph embedding: Uses advanced graph embedding models and mature graph embedding algorithms to represent network structure.
  • Integration with databases: Integrates extensive interaction network databases to obtain gene interaction data.
  • Pathway coverage: Provides two-dimensional visualizations for over 2,000 biological pathways.
  • Interaction characterization: Visualizations highlight genes and illustrate the tightness and nature of their interactions.
  • Dimensionality reduction: Transforms high-dimensional biological data into two-dimensional representations for interpretation.
  • Batch data acquisition: Implements URL optimization features to support efficient batch data acquisition.

Scientific Applications:

  • Pathway visualization: Visualizing and exploring the structure of over 2,000 biological pathways.
  • Interaction analysis: Analyzing interaction tightness and the nature of gene–gene relationships within networks.
  • Network-level interpretation: Enabling interpretation of complex gene interaction systems through dimensionality reduction.
  • Cross-dataset analysis: Supporting batch analyses across multiple datasets via optimized data acquisition.

Methodology:

Applies advanced graph embedding algorithms to interaction network databases to transform high-dimensional gene interaction data into two-dimensional visualizations.

Topics

Details

License:
MIT
Tool Type:
web application, workflow
Programming Languages:
PHP
Added:
6/14/2021
Last Updated:
8/13/2021

Operations

Publications

Liu Y, Zhu Y, He C, Lu Z. BENviewer: a gene interaction network visualization server based on graph embedding model. Database. 2021;2021. doi:10.1093/database/baab033. PMID:34048546. PMCID:PMC8163240.

PMID: 34048546
PMCID: PMC8163240
Funding: - National Key Research and Development Project: 6307030004

Links