BEST

BEST retrieves biomedical entities from the literature to support focused discovery of genes, diseases, drugs, targets, transcription factors, miRNAs, and mutations.

Key Features:

• Direct Entity Retrieval: Returns biomedical entities directly in response to queries instead of lists of articles.
• Real-Time Updates: Continuously updates its database to provide up-to-date results in real time.
• Sophisticated Query Processing: Handles complex queries, including detection of mutations co-occurring with other query terms in the literature.
• Comprehensive Entity Coverage: Reports ten different types of biomedical entities relevant to user queries.

Scientific Applications:

• Drug Discovery and Development: Facilitates identification of relevant drugs and targets referenced in the literature.
• Genetic Research: Enables retrieval of gene–disease associations and co-occurring mutation information.
• Personalized Medicine: Supports finding miRNAs and transcription factors linked to specific diseases.
• Biomedical Research: Provides entity-level information across biomedical literature to support literature-based analyses.

Methodology:

Continuously updates a literature-derived database and processes queries to extract and return biomedical entities, including identification of mutation co-occurrences.