bgc

bgc is a tool to genomic clines using Bayesian statistics. The bgc algorithm uses Markov chain Monte Carlo to estimate the joint posterior probability distribution of the parameters in the Bayesian genomic cline model and designate outlier loci.

Topic

DNA;Statistics and probability;Comparative genomics

Detail

  • Operation: Statistical inference

  • Software interface: Command-line user interface

  • Language: C++

  • License: GNU General Public License >=3

  • Cost: Free

  • Version name: 2.2.0

  • Credit: the National Science Foundation

  • Input: Text files that give the observed allele counts for each individual and locus in the parental and admixed populations.

  • Output: HDF5

  • Contact: C. Alex Buerkle buerkle@uwyo.edu, Zachariah Gompert zgompert@uwyo.edu

  • Collection: -

  • Maturity: Mature

Publications

  • Genomics of isolation in hybrids
  • Gompert Z, Parchman TL, Buerkle CA. Genomics of isolation in hybrids. Philos Trans R Soc Lond B Biol Sci. 2012 Feb 5;367(1587):439-50. doi: 10.1098/rstb.2011.0196. PMID: 22201173; PMCID: PMC3233709.
  • https://doi.org/10.1098/rstb.2011.0196
  • PMID: 22201173
  • PMC: PMC3233709
  • bgc: Software for Bayesian estimation of genomic clines.
  • Gompert Z, Buerkle CA. bgc: Software for Bayesian estimation of genomic clines. Mol Ecol Resour. 2012 Nov;12(6):1168-76. doi: 10.1111/1755-0998.12009.x. Epub 2012 Sep 14. PMID: 22978657.
  • https://doi.org/10.1111/1755-0998.12009.x
  • PMID: 22978657
  • PMC: -
  • Genomic regions with a history of divergent selection affect fitness of hybrids between two butterfly species
  • Gompert Z, Lucas LK, Nice CC, Fordyce JA, Forister ML, Buerkle CA. Genomic regions with a history of divergent selection affect fitness of hybrids between two butterfly species. Evolution. 2012 Jul;66(7):2167-81. doi: 10.1111/j.1558-5646.2012.01587.x. Epub 2012 Feb 23. PMID: 22759293.
  • https://doi.org/10.1111/j.1558-5646.2012.01587.x
  • PMID: 22759293
  • PMC: -

Download and documentation

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