BGMUT

BGMUT catalogs allelic variations in genes encoding human blood group antigens, documenting 1251 alleles across 40 gene loci affecting 30 human blood group systems.

Key Features:

• Comprehensive Allelic Data: Curated entries include detailed information on allelic variations collected from scientific literature and direct submissions by research laboratories.
• Geographic and Ethnic Prevalence Information: When available, reports provide geographic and ethnic distribution data for specific alleles.
• Integration with dbRBC Resource: BGMUT is integrated into the NCBI dbRBC resource for red blood cell biology.

Scientific Applications:

• Transfusion Medicine: Provides allele-level information relevant to blood compatibility assessment and antigen typing.
• Population Genetics and Human Evolution: Supports analyses of allele frequencies, human migrations, and evolutionary relationships among populations.
• Genetic Variation Research: Supplies locus-specific mutation data for studies of gene-specific variation in blood group antigen genes.

Methodology:

Content is manually curated from peer-reviewed publications and direct contributions from research laboratories.