BIKE

BIKE performs Bayesian hierarchical dietary exposure assessments for microbiological and chemical hazards using occurrence and consumption data.


Key Features:

  • Bayesian hierarchical modeling: Implements Bayesian hierarchical models to estimate exposure levels from occurrence and consumption data.
  • OpenBUGS and R integration: Integrates OpenBUGS and R for model specification and statistical computation.
  • Automatic BUGS code generation: Automatically generates specific BUGS code based on provided occurrence and consumption datasets.
  • Chronic exposure support: Supports chronic exposure assessments for chemical contaminants.
  • Acute exposure support: Supports acute exposure assessments for microbiological hazards.
  • Uncertainty and variability estimation: Estimates uncertainty and variability in exposure levels within the Bayesian framework.
  • Optional model structures: Provides several optional model structures to accommodate diverse assessment scenarios.
  • Simulated synthetic data: Includes simulated occurrence and consumption datasets that mimic real-world patterns for example analyses.

Scientific Applications:

  • Chemical hazard exposure assessment: Quantifying chronic dietary exposure to chemical contaminants for risk assessment.
  • Microbiological hazard exposure assessment: Quantifying acute dietary exposure to microbiological hazards for risk assessment.
  • Uncertainty characterization: Characterizing uncertainty and variability in exposure estimates to inform decision making.
  • Model development and testing: Developing and testing exposure models using simulated occurrence and consumption datasets.

Methodology:

Implements Bayesian hierarchical models using OpenBUGS and R, automatically generates BUGS code from occurrence and consumption data, supports multiple optional model structures, and estimates uncertainty and variability in exposure levels.

Topics

Details

License:
Not licensed
Cost:
Free of charge
Tool Type:
workflow
Operating Systems:
Mac, Linux, Windows
Programming Languages:
R
Added:
5/18/2022
Last Updated:
5/18/2022

Operations

Publications

Ranta J, Mikkelä A, Suomi J, Tuominen P. BIKE: Dietary Exposure Model for Foodborne Microbiological and Chemical Hazards. Foods. 2021;10(11):2520. doi:10.3390/foods10112520. PMID:34828801. PMCID:PMC8621415.

PMID: 34828801
PMCID: PMC8621415
Funding: - Maa- ja MetsätalousministeriÖ: 1884/312/2013