Biobase
Biobase provides core data structures and functions for managing and analyzing high-throughput genomic and molecular biology data within the Bioconductor framework.
Key Features:
- Core Bioconductor Infrastructure: Supplies foundational classes and functions used by numerous Bioconductor packages for genomic data analysis.
- High-Throughput Data Structures: Implements standardized data structures for storing and manipulating high-throughput molecular and genomic datasets.
- Interoperability Across Packages: Enables consistent data representation and integration among interoperable Bioconductor packages.
- R-Based Analytical Framework: Integrates with the R statistical programming environment to support computational analysis of genomic datasets.
Scientific Applications:
- Genomic Data Management: Organizes and processes high-throughput genomic and molecular biology datasets.
- Bioinformatics Pipeline Development: Provides standardized data structures supporting integration of multiple Bioconductor analytical tools.
- High-Throughput Data Analysis: Facilitates computational analysis of large-scale genomic experiments.
Methodology:
Biobase implements standardized data classes and analytical functions in the R environment to manage and process high-throughput genomic datasets within interoperable Bioconductor workflows.
Topics
Collections
Details
- License:
- Artistic-2.0
- Cost:
- Free of charge
- Tool Type:
- command-line tool, library
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- R
- Added:
- 1/17/2017
- Last Updated:
- 1/11/2019
Operations
Data Inputs & Outputs
Deposition
Publications
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.