bioCADDIE

bioCADDIE provides indexed search and retrieval of publicly accessible biomedical datasets to enable dataset discovery and reuse.


Key Features:

  • Information Retrieval System: Implements an advanced IR system tailored to retrieving relevant biomedical datasets from a growing repository based on user queries.
  • Utilization of Unstructured Texts: Analyzes unstructured texts such as dataset titles and descriptions to improve retrieval accuracy.
  • Medical Named Entity Extraction: Extracts and categorizes biomedical terms from dataset descriptions to enhance search precision.
  • Deep Learning-Based Word Embeddings: Employs deep learning-derived word embeddings to expand queries with semantically related terms.
  • Re-ranking Strategy: Applies a re-ranking strategy to prioritize datasets according to relevance to expanded queries.

Scientific Applications:

  • Dataset discovery: Facilitates locating publicly accessible biomedical datasets relevant to specific research questions.
  • Dataset reuse for research and validation: Supports reuse of discovered datasets for hypothesis testing and experimental validation in biomedical studies.

Methodology:

Analyzes unstructured text (titles, descriptions), applies medical named entity extraction, uses deep learning-based word embeddings for query expansion, employs re-ranking of search results, and was evaluated in the bioCADDIE Dataset Retrieval Challenge benchmarked against 11 baseline systems using inference Average Precision and inference normalized Discounted Cumulative Gain.

Topics

Details

Programming Languages:
Perl
Added:
1/14/2020
Last Updated:
12/9/2020

Operations

Publications

Wang Y, Rastegar-Mojarad M, Komandur-Elayavilli R, Liu H. Leveraging word embeddings and medical entity extraction for biomedical dataset retrieval using unstructured texts. Database. 2017;2017. doi:10.1093/database/bax091. PMID:31725862. PMCID:PMC7243926.

PMID: 31725862
PMCID: PMC7243926
Funding: - National Institutes of Health: R01GM102282, R01LM011934, U24AI117966