asuri

ASURI discovers marker genes related to risk prediction capabilities and to a clinical variable of interest by implementing subsampling glmnet and unicox for survival analysis.

Key Features:

• Marker Gene Discovery: Identifies genes associated with risk prediction capabilities and a specified clinical variable.
• Risk Score Prediction: Computes patient risk scores based on identified gene signatures.
• Visualization: Generates plots for gene relevance, risk scores, patient stratification, and robust Kaplan-Meier curves.

Scientific Applications:

• Survival Analysis: Discovers survival markers related to clinical phenotypes in patient cohorts.
• Patient Risk Stratification: Stratifies patients by risk based on gene signature-derived scores.

Methodology:

ASURI uses two main steps: subsampling glmnet and unicox.