CoreGx

CoreGx provides foundational functions and classes for pharmacogenomic and radiogenomic analysis packages in the 'Gx' suite, including 'PharmacoGx' and 'RadioGx'.

Key Features:

• CoreSet Class: A base class from which 'RadioSet' and 'PharmacoSet' are derived, with get and set methods for each slot.
• Dose Response Analysis: Functions for fitting and plotting dose response curves.
• Statistical Quantification: Functions for quantifying statistical correlation.
• Curve Metrics: Calculation of area under the curve (AUC) and survival fraction (SF).

Scientific Applications:

• Pharmacogenomics: Foundation for 'PharmacoGx' package analysis of drug response in cancer cell lines.
• Radiogenomics: Foundation for 'RadioGx' package analysis of radiation response.
• Dose Response Modeling: Fitting and visualization of dose-response relationships for therapeutic agents.

Methodology:

Classes and functions abstract shared functionality from other lab package releases to reduce code repetition across 'Gx' suite programs.