crisprShiny

crisprShiny enables interactive visualization and examination of guide RNAs (gRNAs) stored in GuideSet objects to facilitate CRISPR gRNA design and analysis.

Key Features:

• Interactive gRNA Visualization: Renders annotations present in GuideSet objects for interactive exploration of gRNA properties.
• gRNA Examination: Provides functionality to inspect individual gRNAs and their associated annotations.
• gRNA Filtering: Supports filtering of gRNAs based on annotation criteria.
• gRNA Export: Enables export of selected gRNAs for downstream use.
• Modular Architecture: Functions as a self-contained Shiny application or as a module within a larger Shiny app.

Scientific Applications:

• CRISPR gRNA Design: Facilitates the design process by enabling interactive exploration and filtering of candidate gRNAs.
• gRNA Annotation Review: Supports inspection of curated gRNA annotations in GuideSet objects.

Methodology:

The tool implements a Shiny-based graphical interface that operates on GuideSet objects.