crisprViz

crisprViz provides functionalities to visualize and contextualize CRISPR guide RNAs (gRNAs) on genomic tracks across nucleases and applications.

Key Features:

• Genomic track visualization: Plots CRISPR guide RNAs on genomic tracks using the Gviz framework.
• Cross-nuclease compatibility: Visualizes gRNAs across different nucleases and applications.
• Bioconductor integration: Works in conjunction with the crisprBase and crisprDesign Bioconductor packages.

Scientific Applications:

• CRISPR gRNA design validation: Enables contextual visualization of designed gRNAs against genomic coordinates to assess targeting specificity and location.
• Comparative nuclease analysis: Supports visualization of gRNAs for different CRISPR nucleases and editing applications.

Methodology:

Plots are produced using the Gviz framework.