DegNorm

DegNorm performs degradation normalization in bulk RNA-seq data to improve differential expression analysis accuracy.

Key Features:

• Gene-level degradation estimation: Provides degradation estimates for each gene within each sample.
• Degradation normalization: Normalizes bulk RNA-seq data to account for RNA degradation effects.

Scientific Applications:

• Differential expression analysis: Improves the accuracy of differential expression analysis in bulk RNA-seq data by correcting for degradation bias.

Methodology:

The sources do not provide explicit computational methodology details.