DNAcycP2

DNAcycP2 predicts the intrinsic cyclizability of every 50-bp subsequence in a DNA sequence by calculating C-scores from FASTA or text format inputs.

Key Features:

• Sliding window analysis: Evaluates every 50-bp subsequence across the full length of input DNA sequences.
• C-score output: Generates estimated intrinsic cyclizability scores for each 50-bp window in each sequence entry.
• Flexible input formats: Accepts DNA sequences in FASTA or plain text format.

Scientific Applications:

• DNA mechanics research: Quantifies intrinsic cyclizability to study DNA bending and looping properties.
• Genomic sequence analysis: Profiles cyclizability landscapes across genomic regions at 50-bp resolution.

Methodology:

The package computes C-scores as estimated intrinsic cyclizability values for fixed 50-bp subsequences using input DNA sequences provided in FASTA or text format.