easylift

easylift performs genomic liftover operations between different genome assemblies using Bioconductor's GRanges objects and chain files from the UCSC Genome Browser.

Key Features:

• GRanges Integration: Seamlessly works with Bioconductor's GRanges objects for handling genomic ranges across various genome versions.
• Automated Chain File Management: Integrates with the BiocFileCache package to automate the management and caching of chain files necessary for liftover operations.

Scientific Applications:

• Genome Assembly Conversion: Converts genomic coordinates between different genome assemblies without requiring manual specification of chain file paths.

Methodology:

Uses chain files from the UCSC Genome Browser in conjunction with Bioconductor's GRanges objects to perform liftover operations.