enrichViewNet

enrichViewNet visualizes functional enrichment results as network graphs, converting gprofiler2-formatted outputs into Cytoscape networks and enrichment maps that represent gene datasets and associated genes as interconnected nodes.

Key Features:

• Cytoscape Network Generation: Creates customizable Cytoscape networks from gprofiler2-formatted enrichment results where GO terms, pathways, and protein complexes and their associated genes are represented as nodes connected by edges.
• Enrichment Map Creation: Generates enrichment maps that visualize enriched terms as a network with edges connecting overlapping genes.

Scientific Applications:

• Functional Enrichment Visualization: Enables graphical representation of functional enrichment results to interpret relationships between gene datasets and their constituent genes.
• Gene-Dataset Relationship Mapping: Facilitates exploration of how genes connect to multiple GO terms, pathways, or protein complexes through network-based visualization.

Methodology:

The package processes functional enrichment results in gprofiler2 format and constructs network graphs where gene datasets and associated genes serve as nodes with edges representing gene-to-dataset relationships; enrichment maps are generated by connecting enriched terms based on overlapping genes.