graphite

graphite converts pathway topology data from major biological databases into graph objects for network-based analysis.

Key Features:

• Database Integration: Imports pathway topology from KEGG, Panther, PathBank, PharmGKB, Reactome, SMPDB, and WikiPathways databases.
• Graph Object Generation: Produces graph objects that represent pathway structure and relationships for computational analysis.

Scientific Applications:

• Pathway Analysis: Enables network-based approaches to study biological pathway topology and interactions across multiple curated databases.

Methodology:

Pathway topology data is extracted from KEGG, Panther, PathBank, PharmGKB, Reactome, SMPDB, and WikiPathways and converted into graph objects.