HiCool

R generic interface to Hi-C contact matrices in `.(m)cool`, `.hic` or HiC-Pro derived formats, as well as other Hi-C processed file formats. Contact matrices can be partially parsed using a random access method, allowing a memory-efficient representation of Hi-C data in R. The `HiCExperiment` class stores the Hi-C contacts parsed from local contact matrix files. `HiCExperiment` instances can be further investigated in R using the `HiContacts` analysis package.

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License:
MIT
Tool Type:
command-line tool, library
Operating Systems:
Linux, Mac, Windows
Programming Languages:
R
Added:
8/30/2026
Last Updated:
10/2/2026

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