immReferent

immReferent provides a consistent interface for downloading, storing, and accessing immune receptor (TCR/BCR) and HLA sequences from IMGT, IPD-IMGT/HLA, and OGRDB (AIRR-C).

Key Features:

• Reference Data Access: Downloads, stores, and accesses TCR/BCR and HLA sequences from IMGT, IPD-IMGT/HLA, and OGRDB (AIRR-C).
• Tool Export Support: Supports export to MiXCR, TRUST4, Cell Ranger, and IgBLAST.
• Local Caching: Implements local caching for reproducible sequence access.
• Core Dependency: Serves as a core dependency for immunogenomics packages.

Scientific Applications:

• Immunogenomics Analysis: Enables reliable and high-quality immune receptor and HLA sequence access for downstream immunogenomics workflows.
• Reproducible Research: Facilitates reproducible immune receptor analysis through standardized reference data management and local caching.

Methodology:

The package provides a consistent interface for downloading, storing, and accessing reference sequences with local caching for reproducibility.