IsoCorrectoRGUI

IsoCorrectoRGUI provides graphical user interface access to mass spectrometry data correction for stable isotope labeling/tracing metabolomics experiments.

Key Features:

• Natural Isotope Abundance Correction: Corrects mass spectrometry data for natural isotope abundance in metabolomics experiments.
• Tracer Impurity Correction: Corrects mass spectrometry data for tracer isotope impurity in labeling experiments.
• MS and MS/MS Data Support: Handles correction of data from both MS and MS/MS measurements.
• Multiple Tracer Isotope Support: Accommodates any tracer isotope including 13C, 15N, and 18O.
• Multiple-Tracer Experiment Support: Corrects high resolution MS data from experiments using multiple tracers simultaneously such as 13C and 15N.

Scientific Applications:

• Stable Isotope Tracing Metabolomics: Enables accurate quantification of metabolite labeling patterns in tracer-based metabolic studies.
• Mass Spectrometry-Based Metabolomics: Supports correction of both low and high resolution mass spectrometry data for isotope labeling experiments.

Methodology:

Correction algorithms account for natural isotope abundance and tracer impurity in mass spectrometry measurements.