leapR

leapR identifies pathways that are enriched across diverse omics experiments by leveraging tabular expression data using the SummarizedExperiment object.

Key Features:

• Multi-omics compatibility: leapR accepts any tabular expression data including proteomics and transcriptomics.
• SummarizedExperiment integration: leapR uses the SummarizedExperiment object as its data structure for expression data.
• Flexible pathway format support: leapR works with any pathway provided in the .gct file format.

Scientific Applications:

• Pathway enrichment analysis: leapR identifies enriched pathways across diverse omics experiments.

Methodology:

leapR performs layered enrichment analysis of pathways using tabular expression data and pathways in .gct file format.