nearBynding

nearBynding provides a pipeline to discern RNA structure at and proximal to the site of protein binding within regions of the transcriptome defined by the user.

Key Features:

• CLIP Data Input: CLIP protein-binding data can be input as either aligned BAM or peak-called bedGraph files.
• RNA Structure Prediction: RNA structure can either be predicted internally from sequence or users have the option to input their own RNA structure data.
• Profile Comparison: RNA structure binding profiles can be visually and quantitatively compared across multiple formats.

Scientific Applications:

• Transcriptome-wide RNA Structure Analysis: Discern RNA structure at and proximal to protein binding sites within user-defined regions of the transcriptome.

Methodology:

The sources do not provide detailed computational steps or methods beyond the described inputs and outputs.