pathlinkR

pathlinkR facilitates analysis and interpretation of RNA-Seq results by providing tools that take a list of differentially expressed genes and perform multiple analyses on them.

Key Features:

• Pathway Enrichment Analysis: Functions perform pathway enrichment with support for multiple databases.
• Visualization Tools: Functions enable visualization of pathway enrichment results.
• Protein-Protein Interaction Networks: Genes can be used to create and plot protein-protein interaction networks entirely within R.

Scientific Applications:

• RNA-Seq Data Interpretation: Aids in interpreting differential expression results through downstream functional analysis of DE gene lists.
• Pathway Analysis: Identifies enriched biological pathways from RNA-Seq differential expression results using multiple supported databases.
• Network Analysis: Constructs and visualizes protein-protein interaction networks from differentially expressed genes to infer functional relationships.

Methodology:

The package takes a list of differentially expressed genes as input and performs pathway enrichment and protein-protein interaction network analysis with integrated visualization capabilities, all within the R environment.