screenCounter

screenCounter provides functions for counting reads from high-throughput sequencing screen data to quantify barcode abundance.

Key Features:

• Single barcode counting: Supports single barcode quantification in single-end and paired-end sequencing data.
• Combinatorial barcode counting: Supports combinatorial barcode quantification in paired-end sequencing data.

Scientific Applications:

• CRISPR screen analysis: Quantifies barcode abundance from CRISPR screening experiments.
• shRNA screen analysis: Quantifies barcode abundance from shRNA screening experiments.

Methodology:

Read counting from high-throughput sequencing data to quantify barcode abundance.