sesame

SeSAMe provides utilities for analyzing Illumina Infinium DNA methylation arrays across multiple generations of Infinium DNA methylation BeadChips, supporting preprocessing, quality control, visualization and inference for DNA methylation studies.

Key Features:

• Preprocessing: Supports preprocessing of multiple generations of Infinium DNA methylation BeadChips.
• Quality Control: Includes advanced quality control routines for DNA methylation data.
• Detection Calling: Performs accurate detection calling for DNA methylation measurements.
• Inference: Provides intelligent inference of ethnicity and sex from DNA methylation data.
• Visualization: Supports visualization of DNA methylation array data.

Scientific Applications:

• DNA Methylation Analysis: Enables analysis of Illumina Infinium DNA methylation arrays for epigenetic research.
• Epigenetic Inference: Supports inference of sample characteristics including ethnicity and sex from methylation patterns.

Methodology:

Step-wise analysis approach for DNA methylation BeadChips.